It's confusing for users when the Dopesheet's Editor Buttons for Grease Pencil are greyed out.

Can’t create new layers in grease pencil dopesheet

This is often because the 'Only Show Selected' filter is disabled. This 'requirement' does not seem to be necessary since the Dopesheet is already in Grease Pencil mode and there is an active Grease Pencil Object. It is also not apparent as to why so many Operators depend on it and unintuitive that it controls their function. The 'Only Show Selected' filter button is far away from the Operator buttons in the User Interface Header, so it's difficult to make the association.

If the 'Only Show Selected' IS absolutely required, I believe it should be closer to the DOPESHEET_HT_editor_buttons. Otherwise, I think the requirement should be removed.