Blender 2.5 alpha 1 win 32 doesn't load texture image maps with an earlier saved *.blend files - All texture image maps have to be reloaded manually everytime when you load the *.blend file.
blender UI themes can't be saved...
this version is bleeding from millions of scars...
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Looks like a duplicate of http://projects.blender.org/tracker/index.php?func=detail&aid=21238&group_id=9&atid=498
Closing report.