**System Information**
Operating system: Windows 10 Pro
Graphics card: AMD Radeon RX50 OC
**Blender Version**
Broken: 2.83.0
Worked: 2.82
In Texture Paint, changes to the settings and changes to the texture are not saved when you click save. The only way to save them is to close the program and click on "Save before closing?". So you can't save between single working steps when painting textures.
Change something on a texture. Click "Safe". The changes to the texture are not saved. Click Quit, then you get the window "save changes before closing?" with the line "save 1 modified image".